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Differentiating mTOR Inhibitors in Renal Cell Carcinoma
PI3K/Akt/mTOR signalling is dysregulated in many cancers, including renal cell carcinoma (RCC), and activation of this pathway has been suggested to correlate with aggressive behavior and poor prognosis in RCC tumors. mTOR inhibition plays a principal role in the targeted treatment of many cancer ty...
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| Pubblicato in: | Cancer Treat Rev |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957946/ https://ncbi.nlm.nih.gov/pubmed/23433636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2012.12.015 |
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