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Differentiating mTOR Inhibitors in Renal Cell Carcinoma

PI3K/Akt/mTOR signalling is dysregulated in many cancers, including renal cell carcinoma (RCC), and activation of this pathway has been suggested to correlate with aggressive behavior and poor prognosis in RCC tumors. mTOR inhibition plays a principal role in the targeted treatment of many cancer ty...

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Bibliografische gegevens
Gepubliceerd in:Cancer Treat Rev
Hoofdauteurs: Pal, Sumanta K., Quinn, David I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957946/
https://ncbi.nlm.nih.gov/pubmed/23433636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctrv.2012.12.015
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