Requirement for a conserved serine in both processing and joining activities of retroviral integrase.

Retroviruses encode a protein, the integrase (IN), that is required for insertion of the viral DNA into the host cell chromosome. IN alone can carry out the integration reaction in vitro. The reaction involves endonucleolytic cleavage near the 3' ends of both viral DNA strands (the processing s...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Katz, R A, Mack, J P, Merkel, G, Kulkosky, J, Ge, Z, Leis, J, Skalka, A M
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49579/
https://ncbi.nlm.nih.gov/pubmed/1323118
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars