Differential Activation in Amygdala and Plasma Noradrenaline during Colorectal Distention by Administration of Corticotropin-Releasing Hormone between Healthy Individuals and Patients with Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) often comorbids mood and anxiety disorders. Corticotropin-releasing hormone (CRH) is a major mediator of the stress response in the brain-gut axis, but it is not clear how CRH agonists change human brain responses to interoceptive stimuli. We tested the hypothesis that...

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Udgivet i:PLoS One
Main Authors: Tanaka, Yukari, Kanazawa, Motoyori, Kano, Michiko, Morishita, Joe, Hamaguchi, Toyohiro, Van Oudenhove, Lukas, Ly, Huynh Giao, Dupont, Patrick, Tack, Jan, Yamaguchi, Takuhiro, Yanai, Kazuhiko, Tashiro, Manabu, Fukudo, Shin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957789/
https://ncbi.nlm.nih.gov/pubmed/27448273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157347
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