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Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome

BACKGROUND: Corticotropin-releasing hormone (CRH) plays an important role in the pathophysiology of irritable bowel syndrome (IBS) and regulates the stress response through two CRH receptors (R1 and R2). Previously, we reported that a CRHR1 gene polymorphism (rs110402, rs242924, and rs7209436) and h...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Komuro, Hazuki, Sato, Naoko, Sasaki, Ayaka, Suzuki, Naoki, Kano, Michiko, Tanaka, Yukari, Yamaguchi-Kabata, Yumi, Kanazawa, Motoyori, Warita, Hitoshi, Aoki, Masashi, Fukudo, Shin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726564/
https://ncbi.nlm.nih.gov/pubmed/26808377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0147817
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