Corticotropin-Releasing Hormone Receptor 1 Gene Variants in Irritable Bowel Syndrome

BACKGROUND: Corticotropin-releasing hormone (CRH) acts mainly via the CRH receptor 1 (CRH-R1) and plays a crucial role in the stress-induced pathophysiology of irritable bowel syndrome (IBS). Several studies have demonstrated that variants of the CRH-R1 gene carry a potential risk for depression, bu...

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Autors principals: Sato, Naoko, Suzuki, Naoki, Sasaki, Ayaka, Aizawa, Emiko, Obayashi, Takeshi, Kanazawa, Motoyori, Mizuno, Tomoko, Kano, Michiko, Aoki, Masashi, Fukudo, Shin
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434156/
https://ncbi.nlm.nih.gov/pubmed/22957021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042450
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