Tumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging

We previously reported real-time monitoring of cell cycle dynamics of cancer cells throughout a live tumor intravitally using a fluorescence ubiquitination cell cycle indicator (FUCCI). Approximately 90% of cancer cells in the center and 80% of total cells of an established tumor are in G(0)/G(1) ph...

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Veröffentlicht in:Cell Cycle
Hauptverfasser: Yano, Shuya, Takehara, Kiyoto, Zhao, Ming, Tan, Yuying, Han, Qinghong, Li, Shukuan, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
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Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957602/
https://ncbi.nlm.nih.gov/pubmed/27152859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1181240
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