Efficacy of a Cell-Cycle Decoying Killer Adenovirus on 3-D Gelfoam(®)-Histoculture and Tumor-Sphere Models of Chemo-Resistant Stomach Carcinomatosis Visualized by FUCCI Imaging

Stomach cancer carcinomatosis peritonitis (SCCP) is a recalcitrant disease. The goal of the present study was to establish an in vitro-in vivo-like imageable model of SCCP to develop cell-cycle-based therapeutics of SCCP. We established 3-D Gelfoam(®) histoculture and tumor-sphere models of SCCP. FU...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yano, Shuya, Takehara, Kiyoto, Tazawa, Hiroshi, Kishimoto, Hiroyuki, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038935/
https://ncbi.nlm.nih.gov/pubmed/27673332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162991
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