FUCCI Real-Time Cell-Cycle Imaging as a Guide for Designing Improved Cancer Therapy: A Review of Innovative Strategies to Target Quiescent Chemo-Resistant Cancer Cells

Progress in chemotherapy of solid cancer has been tragically slow due, in large part, to the chemoresistance of quiescent cancer cells in tumors. The fluorescence ubiquitination cell-cycle indicator (FUCCI) was developed in 2008 by Miyawaki et al., which color-codes the phases of the cell cycle in r...

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Bibliografiset tiedot
Päätekijät: Shuya Yano, Hiroshi Tazawa, Shunsuke Kagawa, Toshiyoshi Fujiwara, Robert M. Hoffman
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2020-09-01
Sarja:Cancers
Aiheet:
cell cycle
fluorescent proteins
FUCCI
imaging
targeted cancer therapy
quiescent cancer cells
Linkit:https://www.mdpi.com/2072-6694/12/9/2655
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