Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

Quiescent cancer cells are resistant to cytotoxic agents which target only proliferating cancer cells. Time-lapse imaging demonstrated that tumor-targeting Salmonella typhimurium A1-R (A1-R) decoyed cancer cells in monolayer culture and in tumor spheres to cycle from G(0)/G(1) to S/G(2)/M, as demons...

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Vydáno v:Cell Cycle
Hlavní autoři: Yano, Shuya, Zhang, Yong, Zhao, Ming, Hiroshima, Yukihiko, Miwa, Shinji, Uehara, Fuminari, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
Témata:
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615054/
https://ncbi.nlm.nih.gov/pubmed/25483077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.964115
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