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Tumor-targeting Salmonella typhimurium A1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

Quiescent cancer cells are resistant to cytotoxic agents which target only proliferating cancer cells. Time-lapse imaging demonstrated that tumor-targeting Salmonella typhimurium A1-R (A1-R) decoyed cancer cells in monolayer culture and in tumor spheres to cycle from G(0)/G(1) to S/G(2)/M, as demons...

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Bibliografische gegevens
Gepubliceerd in:Cell Cycle
Hoofdauteurs: Yano, Shuya, Zhang, Yong, Zhao, Ming, Hiroshima, Yukihiko, Miwa, Shinji, Uehara, Fuminari, Kishimoto, Hiroyuki, Tazawa, Hiroshi, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615054/
https://ncbi.nlm.nih.gov/pubmed/25483077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.964115
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