Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever

Acute rheumatic fever (ARF) is an autoimmune response to Group A Streptococcus (GAS) infection. Repeated GAS exposures are proposed to ‘prime’ the immune system for autoimmunity. This notion of immune-priming by multiple GAS infections was first postulated in the 1960s, but direct experimental evide...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Raynes, Jeremy M., Frost, Hannah R. C., Williamson, Deborah A., Young, Paul G., Baker, Edward N., Steemson, John D., Loh, Jacelyn M., Proft, Thomas, Dunbar, P. R., Atatoa Carr, Polly E., Bell, Anita, Moreland, Nicole J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957554/
https://ncbi.nlm.nih.gov/pubmed/27499748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01119
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