Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever

Acute rheumatic fever (ARF) is an autoimmune response to Group A Streptococcus (GAS) infection. Repeated GAS exposures are proposed to ‘prime’ the immune system for autoimmunity. This notion of immune-priming by multiple GAS infections was first postulated in the 1960s, but direct experimental evide...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Raynes, Jeremy M., Frost, Hannah R. C., Williamson, Deborah A., Young, Paul G., Baker, Edward N., Steemson, John D., Loh, Jacelyn M., Proft, Thomas, Dunbar, P. R., Atatoa Carr, Polly E., Bell, Anita, Moreland, Nicole J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957554/
https://ncbi.nlm.nih.gov/pubmed/27499748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01119
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