Serological Evidence of Immune Priming by Group A Streptococci in Patients with Acute Rheumatic Fever

Acute rheumatic fever (ARF) is an autoimmune response to Group A Streptococcus (GAS) infection. Repeated GAS exposures are proposed to ‘prime’ the immune system for autoimmunity. This notion of immune-priming by multiple GAS infections was first postulated in the 1960s, but direct experimental evide...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Raynes, Jeremy M., Frost, Hannah R. C., Williamson, Deborah A., Young, Paul G., Baker, Edward N., Steemson, John D., Loh, Jacelyn M., Proft, Thomas, Dunbar, P. R., Atatoa Carr, Polly E., Bell, Anita, Moreland, Nicole J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957554/
https://ncbi.nlm.nih.gov/pubmed/27499748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01119
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