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Group A Streptococcus T Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design

Group A Streptococcus (GAS) (Streptococcus pyogenes) is an important human pathogen associated with significant global morbidity and mortality for which there is no safe and efficacious vaccine. The T antigen, a protein that polymerizes to form the backbone of the GAS pilus structure, is a potential...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Young, Paul G., Raynes, Jeremy M., Loh, Jacelyn M., Proft, Thomas, Baker, Edward N., Moreland, Nicole J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529654/
https://ncbi.nlm.nih.gov/pubmed/30936156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00205-19
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