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Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status

BACKGROUND: Autophagy is a cellular pathway that regulates transportation of cytoplasmic macromolecules and organelles to lysosomes for degradation. Autophagy is involved in both tumorigenesis and tumour suppression. Here we investigated the potential prognostic value of the autophagy-related protei...

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Detalhes bibliográficos
Publicado no:World J Surg Oncol
Main Authors: Schmitz, Klaus Juergen, Ademi, Ceflije, Bertram, Stefanie, Schmid, Kurt Werner, Baba, Hideo Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957418/
https://ncbi.nlm.nih.gov/pubmed/27444698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12957-016-0946-x
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