A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation

Sulforaphane (SFN), a naturally occurring isothiocyanate found in cruciferous vegetables, is implicated as a possible therapy for airway inflammation via induction of the transcription factor NF-E2-related factor 2 (NRF2). In this proof-of-concept clinical study, we show that supplementation of SFN...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Duran, Charity G., Burbank, Allison J., Mills, Katherine H., Duckworth, Heather R., Aleman, Maria M., Kesic, Matthew J., Peden, David B., Pan, Yinghao, Zhou, Haibo, Hernandez, Michelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957339/
https://ncbi.nlm.nih.gov/pubmed/27450419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0406-8
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