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Developmental toxicity assay using high content screening of zebrafish embryos

Typically, time-consuming standard toxicological assays using the zebrafish (Danio rerio) embryo model evaluate mortality and teratogenicity after exposure during the first 2 days post-fertilization. Here we describe an automated image-based high content screening (HCS) assay to identify the teratog...

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Dades bibliogràfiques
Publicat a:J Appl Toxicol
Autors principals: Lantz-McPeak, Susan, Guo, Xiaoqing, Cuevas, Elvis, Dumas, Melanie, Newport, Glenn D., Ali, Syed F., Paule, Merle G., Kanungo, Jyotshna
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957247/
https://ncbi.nlm.nih.gov/pubmed/24871937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3029
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