A carregar...
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
Mutations in the epigenetic modifiers DNMT3A and TET2 non-randomly co-occur in lymphoma and leukemia despite their epistasis in the methylation-hydroxymethylation pathway. Using Dnmt3a and Tet2 double knock-out (DKO) mice in which malignancy development is accelerated, we show that the DKO methylome...
Na minha lista:
| Publicado no: | Nat Genet |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4957136/ https://ncbi.nlm.nih.gov/pubmed/27428748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3610 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|