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An Adaptive Defect Weighted Sampling Algorithm to Design Pseudoknotted RNA Secondary Structures

Computational design of RNA sequences that fold into targeted secondary structures has many applications in biomedicine, nanotechnology and synthetic biology. An RNA molecule is made of different types of secondary structure elements and an important RNA element named pseudoknot plays a key role in...

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Bibliographic Details
Published in:Front Genet
Main Authors: Zandi, Kasra, Butler, Gregory, Kharma, Nawwaf
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956659/
https://ncbi.nlm.nih.gov/pubmed/27499762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00129
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