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An Adaptive Defect Weighted Sampling Algorithm to Design Pseudoknotted RNA Secondary Structures

Computational design of RNA sequences that fold into targeted secondary structures has many applications in biomedicine, nanotechnology and synthetic biology. An RNA molecule is made of different types of secondary structure elements and an important RNA element named pseudoknot plays a key role in...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Zandi, Kasra, Butler, Gregory, Kharma, Nawwaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956659/
https://ncbi.nlm.nih.gov/pubmed/27499762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00129
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