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Structural determinants of HIV-1 Vif susceptibility and DNA binding in APOBEC3F
The human APOBEC3 family of DNA cytosine deaminases serves as a front-line intrinsic immune response to inhibit the replication of diverse retroviruses. APOBEC3F and APOBEC3G are the most potent factors against HIV-1. As a countermeasure, HIV-1 viral infectivity factor (Vif) targets APOBEC3s for pro...
Enregistré dans:
| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956467/ https://ncbi.nlm.nih.gov/pubmed/24185281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3593 |
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