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Synthesis and characterization of a disubstituted piperazine derivative with T-type channel blocking action and analgesic properties
BACKGROUND: T-type calcium channels are important contributors to signaling in the primary afferent pain pathway and are thus important targets for the development of analgesics. It has been previously reported that certain piperazine-based compounds such as flunarizine are able to inhibit T-type ca...
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| Publicado en: | Mol Pain |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SAGE Publications
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956396/ https://ncbi.nlm.nih.gov/pubmed/27053601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916641678 |
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