Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands

BACKGROUND: Both T-type calcium channels and cannabinoid receptors modulate signalling in the primary afferent pain pathway. Here, we investigate the analgesics activities of a series of novel cannabinoid receptor ligands with T-type calcium channel blocking activity. RESULTS: Novel compounds were c...

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Detalhes bibliográficos
Main Authors: You, Haitao, Gadotti, Vinicius M, Petrov, Ravil R, Zamponi, Gerald W, Diaz, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3250956/
https://ncbi.nlm.nih.gov/pubmed/22093952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-89
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