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Prediction of Warfarin Dose in Pediatric Patients: An Evaluation of the Predictive Performance of Several Models

OBJECTIVES: The objective of this study was to evaluate the performance of pediatric pharmacogenetic-based dose prediction models by using an independent cohort of pediatric patients from a multicenter trial. METHODS: Clinical and genetic data (CYP2C9 [cytochrome P450 2C9] and VKORC1 [vitamin K epox...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Marek, Elizabeth, Momper, Jeremiah D., Hines, Ronald N., Takao, Cheryl M., Gill, Joan C., Pravica, Vera, Gaedigk, Andrea, Burckart, Gilbert J., Neville, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956330/
https://ncbi.nlm.nih.gov/pubmed/27453700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-21.3.224
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