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11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored

Dihydrotestosterone (DHT) is regarded as the most potent natural androgen and is implicated in the development and progression of castration resistant prostate cancer (CRPC). Under castrate conditions, DHT is produced from the metabolism of the adrenal androgen precursors, DHEA and androstenedione....

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Pretorius, Elzette, Africander, Donita J., Vlok, Maré, Perkins, Meghan S., Quanson, Jonathan, Storbeck, Karl-Heinz
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956299/
https://ncbi.nlm.nih.gov/pubmed/27442248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159867
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