11-Ketotestosterone and 11-Ketodihydrotestosterone in Castration Resistant Prostate Cancer: Potent Androgens Which Can No Longer Be Ignored

Dihydrotestosterone (DHT) is regarded as the most potent natural androgen and is implicated in the development and progression of castration resistant prostate cancer (CRPC). Under castrate conditions, DHT is produced from the metabolism of the adrenal androgen precursors, DHEA and androstenedione....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pretorius, Elzette, Africander, Donita J., Vlok, Maré, Perkins, Meghan S., Quanson, Jonathan, Storbeck, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956299/
https://ncbi.nlm.nih.gov/pubmed/27442248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159867
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