A pro-nociceptive phenotype unmasked in mice lacking fatty-acid amide hydrolase

Fatty-acid amide hydrolase (FAAH) is the major enzyme responsible for degradation of anandamide, an endocannabinoid. Pharmacological inhibition or genetic deletion of FAAH (FAAH KO) produces antinociception in preclinical pain models that is largely attributed to anandamide-induced activation of can...

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Bibliografski detalji
Izdano u:Mol Pain
Glavni autori: Carey, Lawrence M, Slivicki, Richard A, Leishman, Emma, Cornett, Ben, Mackie, Ken, Bradshaw, Heather, Hohmann, Andrea G
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956176/
https://ncbi.nlm.nih.gov/pubmed/27178246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916649192
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