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Activation of Molecular Signatures for Antimicrobial and Innate Defense Responses in Skin with Transglutaminase 1 Deficiency

Mutations of the transglutaminase 1 gene (TGM1) are a major cause of autosomal recessive congenital ichthyoses (ARCIs) that are associated with defects in skin barrier structure and function. However, the molecular processes induced by the transglutaminase 1 deficiency are not fully understood. The...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Haneda, Takashi, Imai, Yasutomo, Uchiyama, Ryosuke, Jitsukawa, Orie, Yamanishi, Kiyofumi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4956052/
https://ncbi.nlm.nih.gov/pubmed/27442430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159673
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