Expression of IL-33 in ocular surface epithelium induces atopic keratoconjunctivitis with activation of group 2 innate lymphoid cells in mice

In a transgenic mouse line hK14mIL33tg, with the expression of interleukin-33 (IL-33) driven by a keratin 14 promoter, keratoconjunctivitis developed spontaneously between 18 and 22 weeks of age under specific-pathogen-free conditions. These mice showed blepharitis and corneal impairments, and the h...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Imai, Yasutomo, Hosotani, Yuka, Ishikawa, Hiroto, Yasuda, Koubun, Nagai, Makoto, Jitsukawa, Orie, Gomi, Fumi, Nakanishi, Kenji, Yoshimoto, Tomohiro, Nakamura, Takahiro, Yamanishi, Kiyofumi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577277/
https://ncbi.nlm.nih.gov/pubmed/28855579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10227-y
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker