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The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

INTRODUCTION: Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val(66)met genotype, gene expression, and serum levels), (b) early and recent life stre...

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Podrobná bibliografie
Vydáno v:Mol Pain
Hlavní autoři: Generaal, Ellen, Milaneschi, Yuri, Jansen, Rick, Elzinga, Bernet M, Dekker, Joost, Penninx, Brenda WJH
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955993/
https://ncbi.nlm.nih.gov/pubmed/27145806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916646783
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