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The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

INTRODUCTION: Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val(66)met genotype, gene expression, and serum levels), (b) early and recent life stre...

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Publicado en:Mol Pain
Autores principales: Generaal, Ellen, Milaneschi, Yuri, Jansen, Rick, Elzinga, Bernet M, Dekker, Joost, Penninx, Brenda WJH
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955993/
https://ncbi.nlm.nih.gov/pubmed/27145806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916646783
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