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The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

INTRODUCTION: Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val(66)met genotype, gene expression, and serum levels), (b) early and recent life stre...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Generaal, Ellen, Milaneschi, Yuri, Jansen, Rick, Elzinga, Bernet M, Dekker, Joost, Penninx, Brenda WJH
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955993/
https://ncbi.nlm.nih.gov/pubmed/27145806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916646783
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