AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity

Fibrosis is emerging as a hallmark of metabolically dysregulated white adipose tissue (WAT) in obesity. Although adipose tissue fibrosis impairs adipocyte plasticity, little is known about how aberrant extracellular matrix (ECM) remodeling of WAT is initiated during the development of obesity. Here...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Diabetes
Autori principali: Luo, Ting, Nocon, Allison, Fry, Jessica, Sherban, Alex, Rui, Xianliang, Jiang, Bingbing, Xu, X. Julia, Han, Jingyan, Yan, Yun, Yang, Qin, Li, Qifu, Zang, Mengwei
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2016
Soggetti:
Obesity Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955985/
https://ncbi.nlm.nih.gov/pubmed/27207538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1122
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