AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity

Fibrosis is emerging as a hallmark of metabolically dysregulated white adipose tissue (WAT) in obesity. Although adipose tissue fibrosis impairs adipocyte plasticity, little is known about how aberrant extracellular matrix (ECM) remodeling of WAT is initiated during the development of obesity. Here...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Luo, Ting, Nocon, Allison, Fry, Jessica, Sherban, Alex, Rui, Xianliang, Jiang, Bingbing, Xu, X. Julia, Han, Jingyan, Yan, Yun, Yang, Qin, Li, Qifu, Zang, Mengwei
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Obesity Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955985/
https://ncbi.nlm.nih.gov/pubmed/27207538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1122
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