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Inhibiting hexamer disassembly of human UDP-glucose dehydrogenase by photoactivated amino acid crosslinking

The enzyme UDP-glucose dehydrogenase (UGDH) catalyzes the reaction of UDP-glucose to UDP-glucuronate through two successive NAD(+)-dependent oxidation steps. Human UGDH apoprotein purifies as a mixture of dimeric and hexameric species. Addition of substrate and cofactor stabilizes the oligomeric sta...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biochemistry
मुख्य लेखकों: Grady, George, Thelen, Ashley, Albers, Jaleen, Ju, Tong, Guo, Jiantao, Barycki, Joseph J., Simpson, Melanie A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955856/
https://ncbi.nlm.nih.gov/pubmed/27198584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00259
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