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Exploration of GGTase-I substrate requirements. Part 2. Synthesis and biochemical analysis of novel saturated geranylgeranyl diphosphate analogs
Protein prenylation is a type of post-translational modification that aids certain proteins in localizing to the plasma member where they activate cell signaling. To better understand the isoprenoid requirements and differences of FTase and GGTase-I, a series of saturated geranylgeranyl diphosphate...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955811/ https://ncbi.nlm.nih.gov/pubmed/27342751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.06.035 |
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