Control of the innate immune response by the mevalonate pathway

Deficiency of mevalonate kinase (MVK) causes systemic inflammation. However, the molecular mechanisms linking the mevalonate pathway to inflammation remain obscure. Geranylgeranyl pyrophosphate (GGPP), a non-sterol intermediate of the mevalonate pathway, is the substrate for protein geranylgeranylat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Akula, Murali K., Shi, Man, Jiang, Zhaozhao, Foster, Celia E., Miao, David, Li, Annie S., Zhang, Xiaoman, Gavin, Ruth M., Forde, Sorcha D., Germain, Gail, Carpenter, Susan, Rosadini, Charles V., Gritsman, Kira, Chae, Jae Jin, Hampton, Randolph, Silverman, Neal, Gravallese, Ellen M., Kagan, Jonathan C., Fitzgerald, Katherine A., Kastner, Daniel L., Golenbock, Douglas T., Bergo, Martin O., Wang, Donghai
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955724/
https://ncbi.nlm.nih.gov/pubmed/27270400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3487
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados