The cross-talk of LDL-cholesterol with cell motility: Insights from the Niemann Pick Type C1 mutation and altered integrin trafficking

Cholesterol is considered indispensible for the recruitment and functioning of integrins in focal adhesions for cell migration. However, the physiological cholesterol pools that control integrin trafficking and focal adhesion assembly remain unclear. Using Niemann Pick Type C1 (NPC) mutant cells, wh...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Hoque, Monira, Rentero, Carles, Conway, James R, Murray, Rachael Z, Timpson, Paul, Enrich, Carlos, Grewal, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Commentary - Solicited
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955373/
https://ncbi.nlm.nih.gov/pubmed/26366834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2015.1019996
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