The cross-talk of LDL-cholesterol with cell motility: Insights from the Niemann Pick Type C1 mutation and altered integrin trafficking

Cholesterol is considered indispensible for the recruitment and functioning of integrins in focal adhesions for cell migration. However, the physiological cholesterol pools that control integrin trafficking and focal adhesion assembly remain unclear. Using Niemann Pick Type C1 (NPC) mutant cells, wh...

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Vydáno v:Cell Adh Migr
Hlavní autoři: Hoque, Monira, Rentero, Carles, Conway, James R, Murray, Rachael Z, Timpson, Paul, Enrich, Carlos, Grewal, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
Commentary - Solicited
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955373/
https://ncbi.nlm.nih.gov/pubmed/26366834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2015.1019996
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