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Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: Implications for cell migration

Recent work has shown that cadherins at cell-cell junctions bear tensile forces. Using novel FRET-based tension sensors, we showed first that in response to shear stress, endothelial cells rapidly reduce mechanical tension on vascular endothelial (VE)-cadherin. Second, we observed a simultaneous inc...

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Detalhes bibliográficos
Publicado no:Cell Adh Migr
Main Authors: Conway, Daniel E, Schwartz, Martin A
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955370/
https://ncbi.nlm.nih.gov/pubmed/25482618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19336918.2014.968498
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