VE-cadherin and PECAM-1 enhance ALL migration across brain microvascular endothelial cell monolayers

OBJECTIVE: Infiltration of the central nervous system (CNS) by leukemia is a problematic disease manifestation of acute lymphoblastic leukemia (ALL). The mechanisms by which leukocytes interact with brain-derived microvasculature endothelial cells (HBMEnd) and enter the CNS are largely derived from...

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Main Authors: Akers, Stephen M., O'Leary, Heather A., Minnear, Fred L., Craig, Michael D., Vos, Jeffrey A., Coad, James E., Gibson, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929642/
https://ncbi.nlm.nih.gov/pubmed/20470859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.05.001
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