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The promising role of poly(ADP-ribose) polymerase inhibitors in prostate cancer
The TOPARP study showed the beneficial utility of olaparib in a heavily pretreated population of metastatic castration-resistant prostate cancer who were biomarker-positive for aberrations in DNA repair gene. A higher response rate to olaparib of 88% (14 out of 16 patients), time to radiographic pro...
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| Published in: | Asian J Androl |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Medknow Publications & Media Pvt Ltd
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955184/ https://ncbi.nlm.nih.gov/pubmed/26908063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1008-682X.172821 |
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