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Endogenous interleukin‐22 protects against inflammatory bowel disease but not autoimmune cholangitis in dominant negative form of transforming growth factor beta receptor type II mice
During chronic inflammation, interleukin (IL)‐22 expression is up‐regulated in both CD4 and CD8 T cells, exerting a protective role in infections. However, in autoimmunity, IL‐22 appears to have either a protective or a pathogenic role in a variety of murine models of autoimmunity and, by extrapolat...
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| 發表在: | Clin Exp Immunol |
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| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955007/ https://ncbi.nlm.nih.gov/pubmed/27148790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12806 |
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