Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen

AIM: Dexamethasone (DEX) is a widely used synthetic glucocorticoid, which has shown anti-cancer efficacy and anti-estrogenic activity. In this study we explored the possibility that DEX might be used as an endocrine therapeutic agent to treat human non-small cell lung cancer (NSCLC). METHODS: The vi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Acta Pharmacol Sin
Main Authors: Wang, Li-jie, Li, Jian, Hao, Fang-ran, Yuan, Yin, Li, Jing-yun, Lu, Wei, Zhou, Tian-yan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954770/
https://ncbi.nlm.nih.gov/pubmed/27133297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.39
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