Intratumoral estrogen sulfotransferase induction contributes to the anti-breast cancer effects of the dithiocarbamate derivative TM208

AIM: Sulfotransferase-catalyzed sulfation is the most important pathway for inactivating estrogens. Thus, activation of estrogen sulfotransferase (EST) may be an alternative approach for the treatment of estrogen-dependent breast cancer. In this study we investigated the involvement of EST in anti-b...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Ji, Xi-wei, Chen, Guang-ping, Song, Yan, Hua, Ming, Wang, Li-jie, Li, Liang, Yuan, Yin, Wang, Si-yuan, Zhou, Tian-yan, Lu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4814201/
https://ncbi.nlm.nih.gov/pubmed/25937633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.14
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