Apoptosis-Resistant Cardiac Progenitor Cells Modified With Apurinic/Apyrimidinic Endonuclease/Redox Factor 1 Gene Overexpression Regulate Cardiac Repair After Myocardial Infarction

Overcoming the insufficient survival of cell grafts is an essential objective in cell-based therapy. Apurinic/apyrimidinic endonuclease/redox factor 1 (APE1) promotes cell survival and may enhance the therapeutic effect of engrafted cells. The aim of this study is to determine whether APE1 overexpre...

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Publicado en:Stem Cells Transl Med
Autores principales: Aonuma, Tatsuya, Takehara, Naofumi, Maruyama, Keisuke, Kabara, Maki, Matsuki, Motoki, Yamauchi, Atsushi, Kawabe, Jun-ichi, Hasebe, Naoyuki
Formato: Artigo
Lenguaje:Inglês
Publicado: AlphaMed Press 2016
Materias:
Tissue Engineering and Regenerative Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954451/
https://ncbi.nlm.nih.gov/pubmed/27334489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0281
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