An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.

Point mutations in the p53 gene have been detected in a variety of human cancers; the mutations are clustered in four "hot-spots" located in the coding region of exons 5, 7, and 8, which coincide with the four most highly conserved regions of the gene. We report the finding of a heterozygo...

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Detalhes bibliográficos
Main Authors: Sun, Y, Hegamyer, G, Cheng, Y J, Hildesheim, A, Chen, J Y, Chen, I H, Cao, Y, Yao, K T, Colburn, N H
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49532/
https://ncbi.nlm.nih.gov/pubmed/1631151
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