An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma.

Point mutations in the p53 gene have been detected in a variety of human cancers; the mutations are clustered in four "hot-spots" located in the coding region of exons 5, 7, and 8, which coincide with the four most highly conserved regions of the gene. We report the finding of a heterozygous G----C...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sun, Y, Hegamyer, G, Cheng, Y J, Hildesheim, A, Chen, J Y, Chen, I H, Cao, Y, Yao, K T, Colburn, N H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49532/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631151/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.14.6516
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