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Upregulated WDR26 serves as a scaffold to coordinate PI3K/AKT pathway-driven breast cancer cell growth, migration, and invasion

The phosphatidylinositol 3-kinase (PI3K)/AKT pathway transmits signals downstream of receptor tyrosine kinases and G protein-coupled receptors (GPCRs), and is one of the most dysregulated pathways in breast cancer. PI3Ks and AKTs consist of multiple isoforms that play distinct and even opposite role...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Ye, Yuanchao, Tang, Xiaoyun, Sun, Zhizeng, Chen, Songhai
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951255/
https://ncbi.nlm.nih.gov/pubmed/26895380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7439
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