Nuclear β-arrestin1 is a critical cofactor of hypoxia-inducible factor-1α signaling in endothelin-1-induced ovarian tumor progression

Hypoxia-inducible factor-1α (HIF-1α) mediates the response to hypoxia or other stimuli, such as growth factors, including endothelin-1 (ET-1), to promote malignant progression in numerous tumors. The importance of cofactors that regulate HIF-1α signalling within tumor is not well understood. Here we...

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Udgivet i:Oncotarget
Main Authors: Cianfrocca, Roberta, Tocci, Piera, Rosanò, Laura, Caprara, Valentina, Sestito, Rosanna, Di Castro, Valeriana, Bagnato, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951250/
https://ncbi.nlm.nih.gov/pubmed/26909598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7461
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