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T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy
The success of adoptive T cell-based immunotherapy (ACT) in cancer is limited in part by the accumulation of myeloid-derived suppressor cells (MDSC), which block several T cell functions, including T cell proliferation and the expression of various cytotoxic mediators. Paradoxically, the inhibition...
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| 發表在: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Impact Journals LLC
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4951233/ https://ncbi.nlm.nih.gov/pubmed/27007050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8197 |
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