Subpopulations of Myeloid-Derived Suppressor Cells (MDSC) impair T cell responses through independent nitric oxide-related pathways

The accumulation of myeloid-derived suppressor cells (MDSC) in tumor-bearing hosts is a hallmark of malignancy-associated inflammation and a major mediator for the induction of T cell suppression in cancer. MDSC can be divided phenotypically into granulocytic (G-MDSC) and monocytic (Mo-MDSC) subgrou...

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Hauptverfasser: Raber, Patrick L., Thevenot, Paul, Sierra, Rosa, Wyczechowska, Dorota, Halle, Daniel, Ramirez, Maria E., Ochoa, Augusto, Fletcher, Matthew, Velasco, Cruz, Wilk, Anna, Reiss, Krzysztof, Rodriguez, Paulo C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980009/
https://ncbi.nlm.nih.gov/pubmed/24259296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28622
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